High-Sensitivity C-Reactive Protein, Obesity, and Subclinical Atherosclerosis
نویسندگان
چکیده
منابع مشابه
High-sensitivity C-reactive protein, obesity, and subclinical atherosclerosis: implications of JUPITER from the MESA study.
The recent results of Justification for the Use of Statins in Prevention: An Intervention Trial Evaluating Rosuvastatin (JUPITER) trial4 demonstrated that the treatment with rosuvastatin, 20 mg daily, as compared with placebo, was associated with a 44% reduction in the cumulative incidence of major CVD events among 17 802 middle-aged healthy men and women with low levels of low-density lipoprot...
متن کاملRelationship Between C-Reactive Protein and Subclinical Atherosclerosis
Background—Elevated levels of C-reactive protein (CRP) are associated with increased risk for incident cardiovascular events on the basis of observations from several prospective epidemiological studies. However, less is known regarding the relationship between CRP levels and atherosclerotic burden. Methods and Results—We measured CRP in 3373 subjects 30 to 65 years of age who were participatin...
متن کاملC-reactive protein, subclinical atherosclerosis, and risk of cardiovascular events.
C-reactive protein (CRP) is an independent determinant of risk of stroke among both men and women. For instance, in the Framingham Study, the relative risk for future stroke for the highest quartile of CRP compared with the lowest was 2.0 for men and 2.7 for women.1 The association between CRP and risk of stroke among men and women in this cohort persisted after adjustment for age, smoking, tot...
متن کاملClinical and Population Studies Association Between Obesity, High-Sensitivity C-Reactive Protein >2 mg/L, and Subclinical Atherosclerosis Implications of JUPITER from the Multi-Ethnic Study of Atherosclerosis
Objective—High-sensitivity C-reactive protein (hsCRP) levels are closely associated with abdominal obesity, metabolic syndrome, and atherosclerotic cardiovascular disease. The Justification for the Use of Statins in Primary Prevention: An Intervention Trial Evaluating Rosuvastatin (JUPITER) trial has encouraged using hsCRP 2 mg/L to guide statin therapy; however, the association of hsCRP and at...
متن کاملRelationship between High-Density Lipoprotein and C-reactive Protein in Patients with Atherosclerosis
Abstract Background and Objective: Atherosclerosis is an inflammatory disease mostly caused by oxidation of low density lipoproteins (LDLs) while High-density lipoproteins (HDLs) oppose atherosclerosis by inhibiting the oxidation of LDLs. Serum concentration of C- reactive protein (CRP) also increases as an acute phase protein in inflammatory conditions like atherosclerosis. We aimed to evalu...
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ژورنال
عنوان ژورنال: Arteriosclerosis, Thrombosis, and Vascular Biology
سال: 2011
ISSN: 1079-5642,1524-4636
DOI: 10.1161/atvbaha.111.228320